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Surgical Products
The only all-biological valved conduit for use in the aortic position
- The No-React® Aortic BioConduit has the lowest reinfection rate of any biological xenograft and shows reinfection resistance equal to that of homografts The entire valve and conduit is made of biological materials. This is vital, because biological valve with a synthetic sewing ring may resist infection more than a fully mechanical valve, but once the sewing ring becomes involved the infection results in the same pathogenesis as a fully synthetic valve
- No-React® tissues avoid calcification issues in patients of every age—and the advantages are greater for younger patients
- Ten years data shows very low incidence of structural valve deterioration in No-React Conduits, with no incidence of thrombosis, stenosis or calcification. Homografts, on the other hand, have much increased rates of deterioration in the young patient, with a lifetime reoperation risk of 89% for a patient who is 25 at surgery
- CE Approval expected later in 2011 – currently available for Humanitarian Use
No-React® Valved Aortic Conduit
Valve conduits are typically available in three different designs:
1. Mechanical valves in woven polyester fabric conduits (collagen coated and noncoated).
2. Homografts.
3. Xenografts in woven polyester fabric conduits
The BioIntegral No-React BioConduit Aortic Valve Conduit gives surgeons a better alternative. It contains a composite stentless valve, with superior haemodynamics, compared to mechanical valves. Since it is made of only biological materials, the risk of infection can be reduced. The conduit contains a composite porcine valve with excellent haemodynamic properties. The conduit is made of a No-React treated bovine pericardial tube. The risk of infection is reduced because only natural material is used.
There is also no need for anticoagulation therapy
Benefits include :
- Made entirely of biological materials , treated with the No-React® process so the Conduit is very resistant to infection
- Avoids calcification and hence is more durable
- Very low incidence of structural deterioration
- No incidence of thrombosis, stenosis or calcification.
- Excellent Haemodynamics
- Immediately ready for use as no rinsing is required
Materials
Porcine Composite Valve
Bovine Pericardial Tube
